Study suggests linezolid may be as effective as vancomycin for treating patients with complicated skin, soft tissue infections caused by MRSA.

(From "Emergency Medicine Today", April 22 2008)

Medscape (4/21, Berrie) reported that "[t]he oxazolidinone antibiotic linezolid is at least as effective as vancomycin for the treatment of patients with complicated skin and soft tissue infections (cSSTIs) that are proven to be caused by methicillin-resistant Staphylococcus aureus (MRSA), according to" a study presented in Barcelona at the 18th European Congress of Clinical Microbiology and Infectious Diseases. Kamal M. F. Itani, M.D., of the Philadelphia Veteran's Affairs Medical Center, Pennsylvania, and colleagues randomly assigned more than 1,000 "patients...to receive either linezolid (n=544), 600 mg intravenously (IV) or orally every 12 hours, or vancomycin (n=533) IV every 12 hours." These "treatments were continued for seven to 14 days." Dr. Itani said that "[l]inezolid proved to be at least as effective as vancomycin, with higher numerical success rates at" the end of the study "for the treatment of cSSTIs caused by MRSA."

Posted on Tuesday, April 22, 2008 at 09:30AM by

Administrator in National News |

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